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LATE‐ONSET GM2 GANGLIOSIDOSIS PRESENTING AS BURNING DYSESTHESIAS
Author(s) -
Chow GCS,
Clarke JTR,
Banwell BL.
Publication year - 2002
Publication title -
journal of the peripheral nervous system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 67
eISSN - 1529-8027
pISSN - 1085-9489
DOI - 10.1046/j.1529-8027.2002.2008_8.x
Subject(s) - gangliosidosis , sandhoff disease , medicine , gabapentin , dermatology , pathology , disease , alternative medicine
Two brothers with a painful neuropathy as a component of late‐onset GM2 gangliosidosis of the Sandhoff type are presented. A dramatic response of the severe dysesthesias to amitriptyline and gabapentin is described. Symptomatic sensory neuropathy may be a component of late‐onset GM2 gangliosidosis.