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Doppler velocimetry of the uterine and fetal circulations during prostaglandin E 2 , cervical ripening
Author(s) -
Rotmensch S.,
Liberati M.,
Celentano C.,
Bellati U.,
Tiboni G. M.,
BenRafael Z.
Publication year - 1996
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1046/j.1469-0705.1996.08050333.x
Subject(s) - medicine , uterine artery , umbilical artery , middle cerebral artery , fetus , laser doppler velocimetry , placenta , fetal circulation , perfusion , blood flow , prostaglandin e2 , obstetrics , pregnancy , gynecology , gestation , ischemia , biology , genetics
Abstract The objective of the study was to investigate flow characteristics of the maternal uterine and fetal umbilical and middle cerebral arteries following intracervical administration of prostaglandin E 2 (PGE 2 ). Doppler velocimetry of uterine, umbilical and middle cerebral arteries was performed immediately before and 2 h after PGE 2 administration in 28 women with uncomplicated post‐term pregnancy and an unfavorable cervix. Placental position was determined in all cases. When all patients were considered jointly, regardless of placental position, the mean uterine artery resistance index (RI) values were 0.41 ± 0.07 before and 0.48 ± 0.13 2 h after PGE 2 administration ( p < 0.05). When patients with lateral placentas ( n = 20) were analyzed separately, only the non‐placental uterine artery showed a significant increase 2 h after PGE 2 administration, whereas no significant differences were found in the placental uterine artery. No changes were observed in uterine RI values of patients with central placentas. No significant differences were observed for umbilical artery and middle cerebral artery before and after PGE 2 administration. It is concluded that intracervical PGE 2 administration increases uteroplacental resistance but probably does not substantially affect placental perfusion; that the umbilical circulation is not affected; and that there were no signs of redistribution of fetal blood flow. Copyright © 1996 International Society of Ultrasound in Obstetrics and Gynecology

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