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Olivopontocerebellar atrophy: paraneoplastic syndrome of brain tumour?
Author(s) -
Silveri M. C.,
Misciagna S.,
Laudisio A.,
Colosimo C.
Publication year - 2000
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.2000.00071.x
Subject(s) - olivopontocerebellar atrophy , medicine , dysgraphia , cerebellum , pathology , atrophy , lesion , paraneoplastic cerebellar degeneration , cerebellar ataxia , neuroscience , ataxia , degenerative disease , disease , psychology , reading (process) , antibody , psychiatry , political science , law , immunology , autoantibody , dyslexia
We describe a patient who, three years after the onset of an olivopontocerebellar atrophy, developed a right cerebral tumour. The cerebellar symptomatology also included, as in other cerebellar patients previously described, a peripheral dysgraphia. Because this deficit of writing is generally reported in patients with right cerebral lesion, the authors hypothesized that functional alterations of supratentorial structures preceding the tumour by years may be able to damage the neural substrates connecting cerebral and cerebellar structures and to produce cerebellar atrophy.