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Primary progressive aphasia: a case report
Author(s) -
Nagy Tamas Gergely,
Jelencsik Ilona,
Szirmai Imre
Publication year - 1999
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1046/j.1468-1331.1999.640515.x
Subject(s) - primary progressive aphasia , medicine , aphasia , primary (astronomy) , clinical neurology , physical medicine and rehabilitation , neuroscience , psychiatry , pathology , dementia , disease , frontotemporal dementia , psychology , physics , astronomy
We report a 69‐year‐old male patient whose motor aphasia started at the age of 61. The language disability remained isolated and progressed over a period of eight years without any additional cognitive deficits. Computed tomography (CT) and magnetic resonance imaging (MRI) showed moderate cortical atrophy with frontal dominance. Single photon emission tomography (SPECT) showed hypoperfusion in the frontotemporoparietal region, positron emission tomography (PET) demonstrated a global cortical reduction of glucose utilization with a lesser decrement in the occipital lobes. The clinical symptoms and the neuropsychological findings fit the diagnosis of primary progressive aphasia.