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Intra‐operative injection of Patent Blue V dye to facilitate nodal staging in colorectal cancer
Author(s) -
Gandy C. P.,
Biddlestone L. R.,
Roe A. M.,
O'Leary D. P.
Publication year - 2002
Publication title -
colorectal disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.029
H-Index - 89
eISSN - 1463-1318
pISSN - 1462-8910
DOI - 10.1046/j.1463-1318.2002.00391.x
Subject(s) - medicine , colorectal cancer , nodal , lymph , histopathology , lymph node , staining , radiology , cancer , pathology
Objectives Routine histopathology may understage colorectal cancer by failing to detect involved lymph nodes. This study examined the feasibility of dye staining those lymph nodes most likely to harbour metastases. Patients and methods Patent Blue V dye 2.5% was injected intra‐operatively into left‐sided colorectal carcinomas prior to resection in 19 patients. Results Blue‐stained nodes were found in 12/19 patients (63%). Examination of blue‐stained nodes alone correctly identified overall nodal status in 11 (92%) of these 12 patients. Conclusion The technique needs to be refined further. Nonetheless, intra‐operative lymph node staining using blue dye offers the prospect of improving the ease and accuracy of nodal staging in colorectal cancer.