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Adenosarcoma of the uterine corpus associated with ovarian thecoma
Author(s) -
Nomura Kouichi,
Aizawa Shigeo,
Ushigome Shinichiro
Publication year - 2001
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.2001.01259.x
Subject(s) - medicine , pathology , immunohistochemistry , stromal cell , mesenchymal stem cell , estrogen receptor , gynecology , cancer , breast cancer
We describe a case of adenosarcoma of the uterine corpus associated with ovarian thecoma in a 67‐year‐old woman. The patient underwent surgery under a diagnosis of ovarian carcinoma. The 110 × 70 mm‐sized ovarian tumor was diagnosed as thecoma. The polypoid tumor of the uterine corpus which measured 30 × 15 mm was diagnosed as adenosarcoma. Cells of both epithelial and stromal elements of the adenosarcoma expressed estrogen receptors (determined by immunohistochemistry). These findings support the view that estrogen stimulation, including that by a pre‐existing ovarian thecoma, may play a role in the development of mesenchymal and mixed epithelial / mesenchymal uterine tumors, including adenosarcoma.