Premium
Sarcomatoid hepatocellular carcinoma with chondroid variant: Case report with immunohistochemical findings
Author(s) -
Fu Yao,
Kobayashi Shoji,
Kushida Yoshio,
Saoo Kousuke,
Haba Reiji,
Mori Seiji,
Miki Hiroshi,
Ohmori Masaki
Publication year - 2000
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.2000.01133.x
Subject(s) - sarcomatoid carcinoma , pathology , adenocarcinoma , hepatocellular carcinoma , immunohistochemistry , carcinoma , medicine , biology , cancer research , cancer
A case of sarcomatoid hepatocellular carcinoma (HCC) with a chondroid variant in a 72‐year‐old woman is reported. Histologically, the tumor consisted of typical HCC of adult type, with an adenocarcinoma‐like structure and a sarcomatoid component containing multinodular chondroid foci. Transition from carcinoma to sarcomatoid component was observed. The cells containing mucus were extremely few in adenocarcinoma‐like structures. Immunohistochemically, other than typical HCC, some of the chondroid cells, adenocarcinoma‐like cells and sarcomatoid cells were positive for alpha‐fetoprotein.