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Guidelines On The Investigation and Management Of The Antiphospholipid Syndrome
Author(s) -
Greaves M.,
Cohen H.,
Machin S. J.,
Mackie I.
Publication year - 2000
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.2000.02069.x
Subject(s) - antiphospholipid syndrome , epitope , lupus anticoagulant , antibody , cardiolipin , immunology , phospholipid , antigen , autoantibody , phosphatidylserine , chemistry , medicine , biochemistry , membrane
In 1991, the Haemostasis and Thrombosis Task Force of the British Society for Haematology published guidelines on testing for the lupus anticoagulant (LA) (Machin et al, 1991). Since then there have been major developments in our understanding of the nature of `antiphospholipid antibodies' (aPLs) and improvements in our knowledge of the clinical course of the antiphospholipid syndrome. These revised guidelines have been prepared against this background. They cover both clinical and laboratory aspects.