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Spindle‐cell B‐cell lymphoma presenting in the skin
Author(s) -
Goodlad J.R.
Publication year - 2001
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.2001.04323.x
Subject(s) - lymphoma , medicine , cell , dermatology , pathology , biology , genetics
Lymphomas with predominant spindle‐cell morphology have only been previously reported in small numbers; such lesions are potentially mistaken for sarcoma or other spindle‐cell tumours. We describe a 73‐year‐old woman who presented with a tumour on the scalp of a few months’ duration. Biopsy showed a B‐cell lymphoma of follicle centre cell origin with a sarcomatoid appearance and a CD20+, CD10+, CD21+, bcl‐6+ immunophenotype. This case highlights the very rare occurrence of spindle‐cell B‐cell lymphoma presenting in the skin. An awareness of this phenomenon is essential to avoid confusion with a variety of other cutaneous spindle‐cell neoplasms and to enable a correct diagnosis to be made, thereby ensuring that appropriate treatment is initiated.