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Nodular secondary syphilis
Author(s) -
Manuela Papini,
A Bettacchi,
Antonio Guiducci
Publication year - 1998
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1046/j.1365-2133.1998.02191.x
Subject(s) - sarcoidosis , giant cell , medicine , pathology , leprosy , histopathology , differential diagnosis , syphilis , histiocyte , tuberculosis , tuberculoid leprosy , granuloma , secondary syphilis , dermatology , human immunodeficiency virus (hiv) , immunology , lepromatous leprosy
Nodular secondary syphilis in a 23‐year‐old Indian man was characterized by numerous papular, nodular and plaque skin lesions, without involvement of the mucous membranes. The histopathology showed sarcoid‐like granulomata with lymphocytes, histiocytes, eosinophils, plasma cells and multinucleated giant cells. The differential diagnosis included deep mycoses, leprosy, tuberculosis, sarcoidosis and lymphoma. The results of serological tests and the rapid response to penicillin indicated a correct diagnosis.