Diagnostic accuracy of circulating-free DNA for the determination of MYCN amplification status in advanced-stage neuroblastoma: a systematic review and meta-analysis | Zendy

Ricky M. Trigg | Zendy; Suzanne D. Turner | Zendy; Jacqui Shaw | Zendy; Leila Jahangiri | Zendy

Open Access

Diagnostic accuracy of circulating-free DNA for the determination of MYCN amplification status in advanced-stage neuroblastoma: a systematic review and meta-analysis

Author(s) -

Ricky M. Trigg,

Suzanne D. Turner,

Jacqui Shaw,

Leila Jahangiri

Publication year - 2020

Publication title -

british journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.833

H-Index - 236

eISSN - 1532-1827

pISSN - 0007-0920

DOI - 10.1038/s41416-020-0740-y

Subject(s) - diagnostic odds ratio , meta analysis , stage (stratigraphy) , medicine , oncology , bivariate analysis , neuroblastoma , odds ratio , diagnostic accuracy , biology , genetics , statistics , paleontology , mathematics , cell culture

MYCN amplification (MNA) is the strongest indicator of poor prognosis in neuroblastoma (NB). This meta-analysis aims to determine the diagnostic accuracy of MNA analysis in circulating-free DNA (cfDNA) from advanced-stage NB patients.

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