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Fusion and Fission Events in the Endocytic Pathway of Dictyostelium
Author(s) -
Maniak Markus
Publication year - 2003
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1034/j.1600-0854.2003.40101.x
Subject(s) - endocytic cycle , biology , endocytosis , endosome , exocytosis , internalization , microbiology and biotechnology , dictyostelium , fission , lipid bilayer fusion , secretion , biochemistry , cell , membrane , intracellular , gene , physics , quantum mechanics , neutron
The endocytic pathway in Dictyostelium appears as a short circuit between endocytosis and exocytosis. Within the hour that elapses between internalization of nutrients and release of remnants, digestion by lysosomal enzymes occurs. Meanwhile, the maturing endosome undergoes a complex series of fusion and fission events, which change its character profoundly and which are far from being fully understood. This review attempts to order the dynamic events into a sequence of stages that is most consistent with present knowledge .