Open AccessEffects of prandial glycemic changes on objective fetal heart rate parameters
Author(s) -
SERRASERRA VICENTE,
CAMARA ROSA,
SARRIÓN PASCUALA,
JAREÑO MILAGROS,
CERVERA JESÚS,
BELLVER JOSÉ,
PERALES ALFREDO
Publication year - 2000
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1034/j.1600-0412.2000.079011953.x
Subject(s) - medicine , glycemic , post prandial , gestational diabetes , meal , diabetes mellitus , obstetrics , heart rate , endocrinology , pregnancy , gestation , blood pressure , biology , genetics
Background. There is confusion in the literature about the potential effect of maternal glucose levels on the fetal heart rate (FHR) cardiotocographic interpretation. Methods. Study design: prospective clinical descriptive study. Subjects: 21 pregnant women with diabetes mellitus, 23 women with gestational diabetes and 18 healthy non‐diabetic pregnant volunteers (control group). Treatment: maternal capillary glucose measurement and objective FHR analysis (Oxford System 8002) pre‐ and 1 h post‐meal. Statistical analysis: descriptive statistics, Student t ‐tests and Pearson correlation studies. Results. Maternal capillary glucose levels ranged between 2.7–10.5 mmol/l pre‐meal and 4.2–14.8 mmol/l post‐meal. The differences between objective FHR parameters pre‐ and post‐meal were not significant in any of the groups of women studied. No correlation was found between prandial glycemic and FHR changes. Women with optimal and suboptimal glycemic control exhibited similar objective FHR parameters pre‐ and post‐meal. Women with gestational diabetes showed similar prandial cardiotocographic changes irrespective of whether they were on insulin therapy or on hypoglycemic diet only. Conclusions. Objective FHR parameters are unaffected by prandial glycemic changes over a wide range of maternal glucose levels. Timing the non‐stress test in relation to the meals seems irrelevant in clinical practice.