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Increased CD69 expression on peripheral blood eosinophils after specific inhalation challenge
Author(s) -
Pignatti P.,
Perfetti L.,
Galdi E.,
Pozzi V.,
Bossi A.,
Biale C.,
Moscato G.
Publication year - 2002
Publication title -
allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.363
H-Index - 173
eISSN - 1398-9995
pISSN - 0105-4538
DOI - 10.1034/j.1398-9995.2002.23454.x
Subject(s) - cd69 , inhalation , medicine , eosinophil cationic protein , eosinophil , immunology , placebo , cytokine , peripheral , whole blood , flow cytometry , immune system , anesthesia , asthma , t cell , pathology , il 2 receptor , alternative medicine
CD69 is a molecule expressed on human eosinophils after cytokine-activation. Different studies have described the eosinophil activation, evaluated by CD69 expression, at the site of an allergic inflammation. In this study we evaluated the expression of CD69 on peripheral blood eosinophils after a specific inhalation challenge (SIC), in order to better define the state of activation of peripheral blood eosinophils after exposure to sensitizers.