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[IC‐P‐037]: SUBJECTIVE COGNITIVE DECLINE IS ASSOCIATED WITH ALTERED POSTERIOR CINGULATE CONNECTIVITY IN ELDERLY WITH A FAMILIAL HISTORY OF ALZHEIMER's DISEASE
Author(s) -
Verfaillie Sander C.J.,
Binette Alexa Pichet,
VachonPresseau Étienne,
Tabrizi Shirin,
Savard Melissa,
Bellec Pierre,
Ossenkoppele Rik,
Scheltens Philip,
Flier Wiesje M.,
Breitner John C.S.,
Villeneuve Sylvia
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.2309
Subject(s) - default mode network , posterior cingulate , cognition , dementia , boston naming test , cognitive decline , functional magnetic resonance imaging , medicine , effects of sleep deprivation on cognitive performance , audiology , family history , psychology , neuroscience , disease
Figure 2. Connectivity between ROIs within the DMN (A) and connectivity between ROIs and the other ROIs covering the rest of the brain (B). *, p<0.05 adjusted for age, gender, frame displacement. Data are presented as mean+SE. Sander C. J. Verfaillie, Alexa Pichet Binette, Etienne VachonPresseau, Shirin Tabrizi, Melissa Savard, Pierre Bellec, Rik Ossenkoppele, Philip Scheltens, Wiesje M. van der Flier, John C. S. Breitner, Sylvia Villeneuve, Douglas Mental Health University Institute, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada; McGill University Faculty of Medicine, Montreal, QC, Canada; Alzheimer Center and Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands; Centre for Studies on Prevention of Alzheimer’s Disease (StoP-AD Centre), Douglas Mental Health Institute, Montreal, QC, Canada; Northwestern University, Chicago, IL, USA; Centre for Studies on Prevention of Alzheimer’s Disease (StoP-AD Centre), Douglas Hospital Research Centre, Montreal, QC, Canada; Centre for Research, Institute of Geriatric Medicine, Montreal, QC, Canada; McGill University, Montreal, QC, Canada. Contact e-mail: s.verfaillie@vumc.nl