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P3‐179: A comparison of hippocampal volume and integrity: Which is the better predictor of cognitive decline?
Author(s) -
Bruno Davide,
Ciarleglio Adam,
Grothe Michel J.,
Nierenberg Jay,
Bachman Alvin,
Teipel Stefan J.,
Petkova Eva,
Sidtis John,
Adrenkani Babak,
Pomara Nunzio
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.1550
Subject(s) - voxel , hippocampus , hippocampal formation , psychology , atrophy , temporal lobe , dementia , cognitive decline , audiology , medicine , neuroscience , disease , radiology , epilepsy
P1⁄40.00153). According to the cognitive impairment level, a moderate positive correlation was observed in the MCI level (FAST stage: 2-3) (r1⁄40.310, t1⁄42.62, P1⁄40.0109), but no correlation was noted in the dementia level ( FAST stage 4) (r1⁄4-0.0771, t1⁄4-0.604, P1⁄40.548). Conclusions: Since the results of this study indicated that the Z score tends to increase with the FAST stage, the degree of atrophy of the medial temporal region is considered to increase with the severity of Alzheimer’s disease. While the Z score increased with the FAST stage in the MCI group, no correlation was observed between the FAST stage and Z score in the Alzheimer’s disease group. Therefore, the VSRAD was suggested to be useful as an index for the follow-up of patients with MCI.