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IC‐P‐112: Diffusion tensor imaging detected neurodegeneration in preclinical Alzheimer disease
Author(s) -
Wang Qing,
Wang Yong,
Shimony Joshua S.,
Fagan Anne M.,
Cairns Nigel J.,
Ances Beau,
Morris John C.,
Benzinger Tammie L.S.
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.134
Subject(s) - fractional anisotropy , diffusion mri , white matter , medicine , neurodegeneration , dementia , neuroscience , pathology , psychology , disease , magnetic resonance imaging , radiology
ume, cerebral blood flow (both normalized to graymatter cerebellum), gray-matter volume (normalized for intracranial volume), or cortical thickness as dependent variable; diagnostic group (cognitively-normal older adults, MCI patients) as independent variable, adjusted for age and sex. Standardized regression coefficients for effects of diagnostic group are provided with significance indicated (*p<0.05, uncorrected). Negative values reflect hypoperfusion or gray-matter atrophy in MCI patients. Poster Presentations: IC-P P77