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P4‐227: CHARACTERIZATION OF AMINO TERMINAL TRUNCATIONS OF PLAQUE‐ASSOCIATED Aβ AFTER COMBINATION BACE INHIBITOR AND ANTIBODY THERAPY IN AGED PDAPP MICE
Author(s) -
Racke Margaret,
Tzaferis John,
Hole Justin,
Liu Feng,
DeLong Cynthia,
May Patrick,
Hutton Michael,
Nordstedt Christer,
DeMattos Ronald
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.05.1745
Subject(s) - antibody , immunohistochemistry , blot , epitope , combination therapy , chemistry , microbiology and biotechnology , monoclonal antibody , genetically modified mouse , medicine , pharmacology , transgene , pathology , immunology , biochemistry , biology , gene
TRUNCATIONS OF PLAQUE-ASSOCIATED Ab AFTER COMBINATION BACE INHIBITOR AND ANTIBODY THERAPY IN AGED PDAPP MICE Margaret Racke, John Tzaferis, Justin Hole, Feng Liu, Cynthia DeLong, Patrick May, Michael Hutton, Christer Nordstedt, Ronald DeMattos, Eli Lilly and Company, Indianapolis, Indiana, United States; Eli Lilly and Company, Indianapolis, Indiana, United States; Eli Lilly and Company, Indianapolis, Indiana, United States; Eli Lilly and Company, Ltd., Windlesham, United Kingdom; 5 Eli Lilly and Company, Indianapolis, Indiana, United States. Contact e-mail: racke_margaret@ lilly.com