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P4–045: Truncated tau causes microtubule disassembly with aging in tauopathy model mice
Author(s) -
Matsumoto Shinei,
Kambe Taiki,
Motoi Yumiko,
Ishiguro Koichi,
Hasegawa Yukako,
Tabira Takeshi,
Kametani Fuyuki,
Hasegawa Masato,
Hattori Nobutaka
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1433
Subject(s) - tauopathy , microtubule , tau protein , microbiology and biotechnology , tubulin , neurofilament , chemistry , microtubule associated protein , biology , neurodegeneration , immunohistochemistry , pathology , alzheimer's disease , immunology , medicine , disease
P4-045 TRUNCATED TAU CAUSES MICROTUBULE DISASSEMBLY WITH AGING IN TAUOPATHY MODEL MICE Shin-ei Matsumoto, Taiki Kambe, Yumiko Motoi, Koichi Ishiguro, Yukako Hasegawa, Takeshi Tabira, Fuyuki Kametani, Masato Hasegawa, Nobutaka Hattori, Juntendo University School of Medicine, Tokyo, Japan; Juntendo University School of Medicine, Tokyo, Japan; Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan; Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan. Contact e-mail: shimatsu@juntendo.ac.jp