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P2–379: Disconnect between brain and CSF drug exposure and beta‐amyloid levels following BACE inhibition
Author(s) -
Gonzales Cathleen,
Ambroise Claude,
Robshaw Ashley,
Chang Cheng,
HajosKorcsok Eva,
Nolan Charles,
Atchison Kevin,
Doran Shawn,
Brodney Michael,
O'Neill Brian,
Riddell David
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1028
Subject(s) - cerebrospinal fluid , amyloid precursor protein secretase , chemistry , amyloid precursor protein , protease , neprilysin , drug , pharmacology , protease inhibitor (pharmacology) , amyloid (mycology) , amyloid beta , peptide , enzyme , biochemistry , medicine , alzheimer's disease , immunology , disease , human immunodeficiency virus (hiv) , antiretroviral therapy , inorganic chemistry , viral load