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P3‐359: Central BACE1 inhibition by LY2886721 produces opposing effects on APP processing as reflected by cerebrospinal fluid sAPPalpha and sAPPbeta
Author(s) -
Willis Brian,
Martenyi Ferenc,
Dean Robert,
Lowe Stephen,
Nakano Masako,
Monk Scott,
Gonzales Celedon,
Mergott Dustin,
Daugherty Leslie,
Citron Martin,
May Patrick
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2012.05.1584
Subject(s) - cerebrospinal fluid , pharmacodynamics , chemistry , pharmacology , pharmacokinetics , placebo , medicine , endocrinology , amyloid precursor protein , alzheimer's disease , pathology , alternative medicine , disease