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P2‐021: Variable effects of the gamma‐secretase inhibitor ELND006 on Aβ across different compartments (brain, ISF, CSF, and plasma) following sustained exposure via subcutaneous osmotic pumps in wild‐type mice
Author(s) -
Brigham Elizabeth,
Wong Angelina,
Rampurna Gullapalli,
Quinn Kevin,
Kwong Grace,
Willits Christopher,
Wadsworth Angie,
Dofiles Lilibeth,
San Pablo Florentino,
Chian David,
Santiago Pamela,
Hoffman Jennifer,
Cirrito John,
Restivo Jessica,
Goldbach Erich,
Motter Ruth,
Wallace William,
Kinney Gene,
Ness Daniel
Publication year - 2011
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2011.05.911
Subject(s) - microdialysis , interstitial fluid , chemistry , pharmacokinetics , pharmacology , subcutaneous injection , hippocampal formation , medicine , extracellular , biochemistry