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P3‐418: Fbx2‐E3 ligase mediated degradation of BACE1 attenuates Alzheimer amyloidosis and improve synaptic function
Author(s) -
Gong Bing,
Chen Fei,
Pan Yong,
Arrieta-cruz Isabel,
Yoshida Yukiko,
Haroutunian Vahram,
Pasinetti Giulio M.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1961
Subject(s) - ubiquitin ligase , amyloid precursor protein secretase , amyloid precursor protein , microbiology and biotechnology , lysosome , proteasome , ubiquitin , protein degradation , alzheimer's disease , chemistry , biology , biochemistry , medicine , enzyme , gene , disease