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P3‐285: ACAT1 gene ablation increases 24(S)‐hydroxycholesterol content in the brain and ameliorates amyloid pathology in Alzheimer mice
Author(s) -
Rogers Maximillian,
Bryleva Elena,
Chang Catherine,
Buen Floyd,
Harris Brent,
Rousselet Estelle,
Seidah Nabil,
Oddo Salvatore,
LaFerla Frank,
Spencer Thomas,
Hickey William,
Chang Ta Yuan
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.1785
Subject(s) - oxysterol , genetically modified mouse , biology , amyloid precursor protein , immunostaining , amyloid (mycology) , cholesterol , chemistry , transgene , biochemistry , microbiology and biotechnology , endocrinology , medicine , alzheimer's disease , gene , immunohistochemistry , immunology , disease , botany