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P4‐080: Healthy brain aging process demonstrated stable cognitive performances: The osaki‐tajiri project
Author(s) -
Kasuya Masashi,
Meguro Mitsue,
Akanuma Kyoko,
Ishii Hiroshi,
Yamaguchi Satoshi,
Meguro Kenichi
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.04.849
Subject(s) - dementia , cognition , cognitive decline , clinical dementia rating , verbal fluency test , audiology , psychology , fluency , orientation (vector space) , cognitive aging , developmental psychology , gerontology , medicine , cognitive impairment , neuropsychology , psychiatry , disease , mathematics education , geometry , mathematics , pathology
of comprehensive assessments independent of ARCS performance. We performed correlational and stepwise linear regression analyses to explore the association between subtests of the ARCS and tests of corresponding cognitive domains from the formal neuropsychological battery, before and after the addition of either apathy or depression scale scores. Results: The sample comprised 73 individuals including 18 with dementia, 27 with cognitive impairment and 28 without cognitive impairment. Mean patient AES score was 33.4 (SD 8.8) and mean DASS-21 depression score was 11.7 (SD 10.8). Correlations between tests of comparable cognitive domains from ARCS and neuropsychological test battery were: category fluency r1⁄40.58, visuospatial tests r1⁄40.62, delayed verbal recall r1⁄40.71, object naming r1⁄4 0.76, attention r1⁄40.84. Increasing symptoms of apathy or depression had no effect on these associations with only one exception. There were small reductions of performance on ARCS category fluency test relative to category fluency in the neuropsychological test battery. Conclusions: Symptoms of depression or apathy do not appear to be major threats to the validity of unsupervised cognitive testing using the ARCS.