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P2‐413: Effect of memantine treatment on regional cortical metabolism in Alzheimer's disease
Author(s) -
Sultzer David L.,
Melrose Rebecca J.,
Harwood Dylan G.,
Campa Olivia,
Bussel Natalya,
Mandelkern Mark A.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.1492
Subject(s) - memantine , medicine , clinical dementia rating , rating scale , temporal cortex , dementia , psychology , neuroscience , disease , developmental psychology
(0.73%) patient. Noticeable cognitive deterioration was reported by caregivers in 12 (8.8%) patients during the first month of treatment. Conclusions: Next-day crossover from galantamine ER (Razadyne ER) to rivastigmine patch (Exelon Patch) was well tolerated. Cognitive deterioration was reported by caregivers in 8.8% of patients whose treatment were switched from galantamine ER to rivastigmine patch 4.6mg/day.