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Mid‐trimester abortion using prostaglandin E 2 gel
Author(s) -
Herabutya Y.,
Israngura Na Ayudthaya N.
Publication year - 1991
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(91)90233-u
Subject(s) - medicine , abortion , prostaglandin , pregnancy , obstetrics , hypertonic saline , prostaglandin e2 , gestational age , products of conception , saline , first trimester , gestation , gynecology , anesthesia , endocrinology , genetics , biology
Abstract Nineteen cases of mid‐trimester pregnancy were terminated using prostaglandin E 2 gel applied intracervically. In this prospective study, 42% were primipara with gestational age at the time of abortion between 16 and 28 weeks. The induction to abortion time was 19.65 ± 10.37 h with a success rate of 89%. The average number of applications was 1.8 times (range 1–3 times) and the average dosage of prostaglandin required was 5.5 mg (range 3–9 mg). The complications were minimal except retained placenta in 42% of cases. Prostaglandin E 2 in form of gel applied intracervically is an effective alternative to the commonly used hypertonic saline or, more recently, to prostaglandin analogues for termination of pregnancy in the second trimester.