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Control of tubulin gene expression during metacyclogenesis of Trypanosoma cruzi
Author(s) -
Rondinelli Edson,
de Moura-Neto Rodrigo Soares,
Suva Rosane,
de Almeida Soares Célia Maria,
Carvalho José Francisco,
de Castro Firmino Torres
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)81053-5
Subject(s) - trypanosoma cruzi , tubulin , gene expression , biology , gene , microbiology and biotechnology , microtubule , chemistry , genetics , parasite hosting , computer science , world wide web
During differentiation of the dividing epimastigote to the non‐dividing metacyclic trypomastigote form of the parasitic protozoan Trypanosoma cruzi there is a marked reduction in the rate of synthesis of the major proteins α‐ and β‐tubulin. Our results indicate that the control of synthesis of these proteins during the differentiation event is exerted at the level of α‐ and β‐tubulin mRNA accumulation.