Viral CNS infections in children from a malaria-endemic area of Malawi: a prospective cohort study | Zendy

Macpherson Mallewa | Zendy; Pamela Vallely | Zendy; Brian Faragher | Zendy; Dan Banda | Zendy; Paul E. Klapper | Zendy; Mavuto Mukaka | Zendy; Harriet Khofi | Zendy; Paul Pensulo | Zendy; Terrie E. Taylor | Zendy; Malcolm E. Molyneux | Zendy; Tom Solomon | Zendy

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Viral CNS infections in children from a malaria-endemic area of Malawi: a prospective cohort study

Author(s) -

Macpherson Mallewa,

Pamela Vallely,

Brian Faragher,

Dan Banda,

Paul E. Klapper,

Mavuto Mukaka,

Harriet Khofi,

Paul Pensulo,

Terrie E. Taylor,

Malcolm E. Molyneux,

Tom Solomon

Publication year - 2013

Publication title -

the lancet global health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.97

H-Index - 88

eISSN - 2572-116X

pISSN - 2214-109X

DOI - 10.1016/s2214-109x(13)70060-3

Subject(s) - cerebral malaria , medicine , malaria , plasmodium falciparum , prospective cohort study , virology , immunology , cohort , pediatrics

Fever with reduced consciousness is an important cause of hospital admission of children in sub-Saharan Africa, with high mortality. Cerebral malaria, diagnosed when acute Plasmodium falciparum infection and coma are recorded with no other apparent reason, is one important cause. We investigated whether viruses could also be an important cause of CNS infection in such patients, and examined the relative contribution of viral pathogens and malaria parasitaemia.

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