Open AccessIonic basis of a differential effect of adenosine on refractoriness in rabbit AV nodal and atrial isolated myocytes
Author(s) -
Antony J. Workman
Publication year - 1999
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1016/s0008-6363(99)00166-2
Subject(s) - refractory period , adenosine , electrophysiology , nodal , effective refractory period , membrane potential , medicine , patch clamp , myocyte , chemistry , biophysics , endocrinology , cardiology , biology
Firstly, to compare effects of adenosine on membrane potential and refractoriness in AV nodal and atrial cells. Secondly, to assess the contribution of the effects of adenosine on IKAdo and ICaL to its effects on the functional electrophysiological properties in the two cell types.
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