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A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates
Author(s) -
Juliana Souza Ribeiro Costa,
Karen de Oliveira Cruvinel,
Laura de Oliveira Nascimento
Publication year - 2019
Publication title -
journal of advanced research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.659
H-Index - 55
eISSN - 2090-1232
pISSN - 2090-1224
DOI - 10.1016/j.jare.2019.04.010
Subject(s) - buccal administration , drug , medicine , critical quality attributes , swallowing , wafer , drug delivery , pharmacology , computer science , biomedical engineering , dentistry , nanotechnology , materials science , operations management , engineering , downstream (manufacturing)
Highlights • This mini-review provides a thorough overview of current buccal/oral lyophilizates.• The mini-review discusses material and process parameters using the quality by design (QbD) approach.• This study covers trends in experimental buccal/oral formulations.• It relates drug and dosage form limitations to aid future developments.• It shows buccal/oral lyophilizates as safe and effective prominent drug delivery systems.

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