Open Accessc-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder
Author(s) -
Pablo S. Contreras,
Pablo Tapía,
Lila González-Hódar,
Ivana Peluso,
Chiara Soldati,
Gennaro Napolitano,
Maria Matarese,
Macarena Las Heras,
Cristian Valls,
Alexis Martínez,
Elisa Balboa,
Juan Francisco Castro,
Nancy Leal,
Frances M. Platt,
Andrzej Sobota,
Dominic Winter,
Andrés D. Klein,
Diego L. Medina,
Andrea Ballabio,
Alejandra Álvarez,
Silvana Zanlungo
Publication year - 2020
Publication title -
iscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.805
H-Index - 27
ISSN - 2589-0042
DOI - 10.1016/j.isci.2020.101691
Subject(s) - tfeb , microbiology and biotechnology , autophagy , lysosome , basic helix loop helix leucine zipper transcription factors , biology , regulator , endocytosis , phosphorylation , tyrosine kinase , chemistry , signal transduction , cancer research , transcription factor , biochemistry , gene , cell , enzyme , apoptosis , dna binding protein
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