Relapse of herpes simplex encephalitis in a patient with metastatic small cell lung cancer following scalp sparing whole brain radiotherapy | Zendy

Abdullah Balkhair | Zendy; A. Al Wahaibi | Zendy; Sameer Raniga | Zendy; M. Al Amin | Zendy; Fatma Ba Alawi | Zendy; Mortada El-Tigani | Zendy; Shiyam Kumar | Zendy

Open Access

Relapse of herpes simplex encephalitis in a patient with metastatic small cell lung cancer following scalp sparing whole brain radiotherapy

Author(s) -

Abdullah Balkhair,

A. Al Wahaibi,

Sameer Raniga,

M. Al Amin,

Fatma Ba Alawi,

Mortada El-Tigani,

Shiyam Kumar

Publication year - 2019

Publication title -

idcases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.319

H-Index - 13

ISSN - 2214-2509

DOI - 10.1016/j.idcr.2019.e00626

Subject(s) - medicine , encephalitis , herpes simplex virus , dexamethasone , radiation therapy , brain metastasis , chemotherapy , lung cancer , cancer , virus , immunology , metastasis

Highlights • Late virologic relapse of Herpes simplex virus encephalitis [HSE] is a scarcely reported clinical entity.• We report a case of HSE with late virologic relapse in a patient with metastatic small cell lung cancer.• Possible association between cranial radiotherapy and dexamethasone with subsequent risk of HSE and relapse is exemplified.• We propose antiviral prophylaxis for at-risk immunocompromised patients receiving dexamethasone or whole brain radiotherapy.• We emphasised the seriousness of virologic relapse of HSE in immunocompromised patients.

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