
Application of 2H stable isotope labelling methodology and ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry for the metabolite identification of dehydroandrographolide in rats
Author(s) -
Pengpeng Bai,
Kaixia Niu,
Zhipeng Huo,
Xinchi Feng,
Feng Qiu
Publication year - 2022
Publication title -
analytical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.392
H-Index - 73
eISSN - 1348-2246
pISSN - 0910-6340
DOI - 10.1007/s44211-022-00129-z
Subject(s) - chemistry , glucuronidation , chromatography , in vivo , hydroxylation , metabolite , glucuronide , metabolism , biotransformation , mass spectrometry , pharmacokinetics , biochemistry , in vitro , microsome , pharmacology , enzyme , microbiology and biotechnology , biology , medicine