Open AccessInvestigation of the synergistic effect of glimepiride and rosuvastatin on alloxan-induced diabetic rat
Author(s) -
Debashish Mondol,
Md. Nahinul Islam,
Sonchita Biswas,
Protic Jodder,
Samiron Sana,
Md. Abu Saleh,
Md. Rafiqul Islam
Publication year - 2020
Publication title -
journal of diabetes and metabolic disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 33
ISSN - 2251-6581
DOI - 10.1007/s40200-020-00662-6
Subject(s) - glimepiride , dyslipidemia , rosuvastatin , medicine , lipid profile , alloxan , diabetes mellitus , endocrinology , body weight , blood lipids , type 2 diabetes mellitus , pharmacology , cholesterol
Diabetes mellitus is characterized by having a multitude of life-threatening secondary complications, particularly dyslipidemia, which ultimately leads to the development of comorbid diseases, such as cardiovascular diseases. This research work was designed to investigate the synergistic effect of glimepiride (1 mg/kg b.w.) and rosuvastatin (10 mg /kg b.w.) on alloxan-induced diabetic rats having dyslipidemia.