Open AccessFunctional Analysis of Induced Human Ballooned Hepatocytes in a Cell Sheet-Based Three Dimensional Model
Author(s) -
Botao Gao,
Katsuhisa Sakaguchi,
Tetsuya Ogawa,
Y. Kagawa,
Hirotsugu Kubo,
Tatsuya Shimizu
Publication year - 2021
Publication title -
jo'jig gonghag gwa jaesaeng uihag/tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 23
eISSN - 2212-5469
pISSN - 1738-2696
DOI - 10.1007/s13770-020-00297-x
Subject(s) - hepatocyte , bone canaliculus , fibroblast , embryonic stem cell , bile acid , cell , biology , microbiology and biotechnology , medicine , endocrinology , biochemistry , in vitro , gene
Ballooned hepatocytes (BH) are a key histological hallmark of nonalcoholic steatohepatitis (NASH), yet their consequences for liver-specific functions are unknown.