Open AccessHigh-Efficiency Cationic Labeling Algorithm of Macroaggregated Albumin with 68Gallium
Author(s) -
Ayşe Uğur,
Aziz Gültekin,
Doğangün Yüksel
Publication year - 2021
Publication title -
nuclear medicine and molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.534
H-Index - 23
eISSN - 1869-3482
pISSN - 1869-3474
DOI - 10.1007/s13139-021-00687-6
Subject(s) - elution , cationic polymerization , chromatography , borax , medicine , radiochemistry , nuclear chemistry , chemistry , organic chemistry , raw material
The generator product radionuclide gallium-68( 68 Ga) is widely used for PET/CT imaging agents and the 68 Ga-labeled MAA is an attractive alternative to 99m Tc-labeled MAA. Using a commercially available MAA labeling kit for 99m Tc, we presented a reliable synthesis protocol with a highly efficient, organic solvent-free cationic method in GMP conditions in the Scintomics automated synthesis unit.