Open AccessMolecular Analysis as a Guide to Determining the Extent and Pathophysiology of Perilesional Tissues in Oral Epithelial Dysplasias
Author(s) -
Meenakshi Singhal,
Ankita Tandon,
Saurabh Juneja,
Devi Charan Shetty,
Sanjeev Kumar,
Abhishek Jain
Publication year - 2019
Publication title -
journal of maxillofacial and oral surgery/journal of maxillofacial and oral surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.293
H-Index - 21
eISSN - 0974-942X
pISSN - 0972-8279
DOI - 10.1007/s12663-019-01303-z
Subject(s) - immunohistochemistry , pathology , medicine , epithelial dysplasia , dysplasia , epithelium , oral mucosa , carcinoma , biopsy
Clinically and histologically normal appearing perilesional mucosa of epithelial dysplasia may harbor early genetic changes. Hence, the present study is designed to determine the early molecular changes in the form of p16 and EGFR immunoexpressions in perilesional tissues.