Open AccessMultiparametric MR-PET measurements in hypermetabolic regions reflect differences in molecular status and tumor grade in treatment-naïve diffuse gliomas
Author(s) -
Hiroyuki Tatekawa,
Akifumi Hagiwara,
Hiroyuki Uetani,
Jingwen Yao,
Talia C. Oughourlian,
Shadfar Bahri,
Chencai Wang,
Catalina Raymond,
Albert Lai,
Timothy F. Cloughesy,
Phioanh Leia Nghiemphu,
Linda M. Liau,
Whitney Pope,
Noriko Salamon,
Benjamin M. Ellingson
Publication year - 2020
Publication title -
journal of neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.256
H-Index - 114
eISSN - 1573-7373
pISSN - 0167-594X
DOI - 10.1007/s11060-020-03613-6
Subject(s) - medicine , nuclear medicine , pathology
To assess whether hypermetabolically-defined regions of interest (ROIs) on 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (PET) could be used to evaluate physiological features and whether there are measurable differences between molecular subtypes and tumor grades.