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Spatial and temporal changes in the expression of steroid hormone receptors in mouse model of endometriosis
Author(s) -
Anuradha Mishra,
Mosami Galvankar,
Neha Singh,
Deepak Modi
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01725-6
Subject(s) - endometrium , endometriosis , estrogen receptor , stromal cell , endocrinology , receptor , medicine , biology , estrogen , steroid hormone , progesterone receptor , steroid hormone receptor , hormone , cancer , breast cancer
Endometriosis is recognized as a steroid hormone-dependent disorder. However, controversies exist regarding the status of the steroid hormone receptor expression in endometriotic tissues. The purpose of this study was to determine the ontogeny of cellular changes in the expression of estrogen receptors (ERα, ERβ), G protein-coupled estrogen receptor 1 (GPER1), and progesterone receptors (PRs) in endometriosis using a mouse model.

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