Open AccessComparison of liquid-based to tissue-based biopsy analysis by targeted next generation sequencing in advanced non-small cell lung cancer: a comprehensive systematic review
Author(s) -
Stepan M. Esagian,
Georgia Grigoriadou,
Ilias P. Nikas,
Vasileios Boikou,
Peter M. Sadow,
Jae Kyung Won,
Konstantinos P. Economopoulos
Publication year - 2020
Publication title -
journal of cancer research and clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.338
H-Index - 94
eISSN - 1432-1335
pISSN - 0171-5216
DOI - 10.1007/s00432-020-03267-x
Subject(s) - liquid biopsy , kras , biopsy , medicine , lung cancer , cancer , cochrane library , oncology , pathology , meta analysis , colorectal cancer
To explore whether targeted next generation sequencing (NGS) of liquid biopsy in advanced non-small cell lung cancer (NSCLC) could potentially overcome the innate problems that arise with standard tissue biopsy, like intratumoral heterogeneity and the inability to obtain adequate samples for analysis.