Open AccessLongitudinal changes in the macula and optic nerve in familial dysautonomia
Author(s) -
Jonathan Kfir,
Mengfei Wu,
Mengling Liu,
Leela Raju,
Joel S. Schuman,
Hiroshi Ishikawa,
M. Isabel Vanegas,
Carlos E. MendozaSantiesteban,
JoseAlberto Palma,
Horacio Kaufmann,
Barr Morgenstein,
Gadi Wollstein
Publication year - 2020
Publication title -
journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 136
eISSN - 1432-1459
pISSN - 0340-5354
DOI - 10.1007/s00415-020-10298-4
Subject(s) - medicine , ophthalmology , nerve fiber layer , retinal , optic nerve , optical coherence tomography , optic disk , ganglion , anatomy
Familial Dysautonomia (FD) disease, lacks a useful biomarker for clinical monitoring. In this longitudinal study we characterized the structural changes in the macula, peripapillary and the optic nerve head (ONH) regions in subjects with FD.