Open AccessMaternal fish oil consumption has a negative impact on mammary gland tumorigenesis in C3(1) Tag mice offspring
Author(s) -
Gabriela Ion,
Juliana A. Akinsete,
Theodore R. Witte,
Marinela Bostan,
W. Elaine Hardman
Publication year - 2021
Publication title -
european journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.321
H-Index - 96
eISSN - 1436-6215
pISSN - 1436-6207
DOI - 10.1007/s00394-021-02546-8
Subject(s) - fish oil , offspring , mammary gland , weaning , biology , lactation , corn oil , endocrinology , medicine , pregnancy , andrology , cancer , breast cancer , fish <actinopterygii> , genetics , fishery
Omega-3 fatty acids have been shown to reduce the incidence and slow the growth of mammary gland cancer in rodent models. Since exposure to dietary components during the critical developmental times of gestation and lactation may alter risk for mammary gland cancer in females, we tested whether exposure to increased levels of long-chain omega-3 fatty acids from fish oils would be preventive or promotional to mammary gland cancer in the offspring.