Open AccessHold-down as an alternative to unit dose in cocaine self-administration experiments: Characterization using a progressive ratio schedule
Author(s) -
David C. S. Roberts,
Benjamin Zimmer
Publication year - 2020
Publication title -
psychopharmacology/psychopharmacologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.378
H-Index - 196
eISSN - 1432-2072
pISSN - 0033-3158
DOI - 10.1007/s00213-020-05565-1
Subject(s) - self administration , drug , psychology , pharmacology , medicine , bolus (digestion) , stimulus (psychology) , anesthesia , psychotherapist
Virtually all cocaine self-administration studies have used a "unit dose" as a reinforcing stimulus; the subject is a passive recipient of an experimenter-selected dose.