Long term survival analysis: Breast cancer and age at diagnosis | Zendy

Marubini E. | Zendy; Mezzanotte G. | Zendy; Boracchi P. | Zendy; Veronesi U. | Zendy

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Long term survival analysis: Breast cancer and age at diagnosis

Author(s) -

Marubini E.,

Mezzanotte G.,

Boracchi P.,

Veronesi U.

Publication year - 1990

Publication title -

statistics in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.996

H-Index - 183

eISSN - 1097-0258

pISSN - 0277-6715

DOI - 10.1002/sim.4780090704

Subject(s) - breast cancer , allowance (engineering) , medicine , relative survival , poisson regression , cancer , demography , poisson distribution , survival analysis , multiplicative function , term (time) , statistics , oncology , mathematics , population , cancer registry , mechanical engineering , mathematical analysis , environmental health , quantum mechanics , sociology , engineering , physics

The role of age at surgery of breast cancer patients as a determinant of relative survival after making allowance for clinical profile was investigated on a case series of 716 women followed for more than 20 years in one single institution. Multiplicative and additive models for grouped data were adopted to model the standardized mortality ratio and the excess death rate respectively. The models were fitted by the GLIM system assuming a Poisson error function. We conclude that operable breast cancer has a relatively lower impact on total mortality in older patients (65 years or more) than in younger ones and, moreover, the older patients have a more favourable course.

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