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Assay of rotenone in river water by high‐throughput tandem mass spectrometry and multiple‐reaction monitoring methodology
Author(s) -
Di Donna Leonardo,
Mazzotti Fabio,
Sindona Giovanni,
Tagarelli Antonio
Publication year - 2005
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1953
Subject(s) - chemistry , analyte , atmospheric pressure chemical ionization , selected reaction monitoring , chromatography , mass spectrometry , rotenone , chemical ionization , tandem mass spectrometry , tandem , analytical chemistry (journal) , throughput , ionization , ion , organic chemistry , telecommunications , biochemistry , materials science , wireless , composite material , computer science , mitochondrion
The high‐throughput analytical approach proposed for the assay of rotenone in lake and river waters presented here is based on atmospheric pressure chemical ionization (APCI) multiple‐reaction monitoring (MRM) methodology whereby the analyte and internal standard solutions are directly analyzed, without any previous chromatographic separation. The very good accuracy is obtained by the critical choice of a reference compound that shows gas‐phase chemistry similar to that of the analyte, by producing the same product ions selected for the MRM‐based assay. Copyright © 2005 John Wiley & Sons, Ltd.
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