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Ion optical considerations in tandem mass spectrometry
Author(s) -
Boerboom A. J. H.
Publication year - 1990
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290041009
Subject(s) - chemistry , tandem , mass spectrometry , hybrid mass spectrometer , quadrupole mass analyzer , triple quadrupole mass spectrometer , tandem mass spectrometry , analytical chemistry (journal) , quadrupole , resolution (logic) , ion , acceleration , selected reaction monitoring , chromatography , atomic physics , physics , aerospace engineering , organic chemistry , classical mechanics , artificial intelligence , computer science , engineering
A review of tandem sector‐field mass spectrometers is given with features of various combinations of electric and magnetic sector fields and quadrupole lenses and, eventually, a Wien filter. In particular, a tandem mass spectrometer is described, constructed at Amsterdam, with post‐acceleration, variable dispersion and array detection. The simultaneously‐detected mass range varies from 1:1.06 through 1:12, the resolution in the second stage amounts to 1000 (single‐focusing), the dynamic range is 5000:1, and the sensitivity is such that less than 1 fmol of sample can be detected and identified.
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