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Evaluation of anxiolytic activity of spray dried powders of two South Brazilian Passiflora species
Author(s) -
Reginatto Flávio H.,
DeParis Fernanda,
Petry Raquel D.,
Quevedo João,
Ortega George González,
Gosmann Grace,
Schenkel Eloir P.
Publication year - 2006
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1853
Subject(s) - passiflora , anxiolytic , traditional medicine , elevated plus maze , chemistry , medicine , botany , biology , biochemistry , anxiety , receptor , psychiatry
The Passiflora extracts have been used in folk medicine because of its reputed sedative and anxiolytic properties. The present study aimed to compare the potential anxiolytic activity of two Passiflora spray‐dried powders obtained from P. alata and P. edulis , known in Brazil as ‘maracujá’. Male adult Swiss rats were treated with 200, 400 and 800 mg/kg of spray‐dried powders p.o. and anxiolytic activity was evaluated using the elevated plus‐maze test. The spray‐dried powders showed anxiolytic activity in doses of 400 and 800 mg/kg. Our results support the potential anxiolytic effect of Passiflora spray‐dried powders ( P. alata and P. edulis ). Copyright © 2006 John Wiley & Sons, Ltd.
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