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Proteomics in ocular fluids
Author(s) -
Grus Franz H.,
Joachim Stephanie C.,
Pfeiffer Norbert
Publication year - 2007
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.200700105
Subject(s) - glaucoma , tears , ophthalmology , aqueous humor , medicine , macular degeneration , diabetic retinopathy , uveitis , disease , proteomics , pathology , immunology , chemistry , diabetes mellitus , endocrinology , biochemistry , gene
Abstract The focus of this article is to review recent techniques in proteomic analysis of ocular fluids. These fluids include tears, aqueous humor, and vitreous, they will also be compared to serum analysis. Furthermore, we attempt to summarize some disease correlated biomarkers in ocular fluids that were discovered through different proteomic techniques in eye diseases like dry eye, glaucoma, age‐related macular degeneration, uveitis, or diabetic retinopathy. This review is trying to point out the importance of these biomarkers for clinical applications.