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Front Cover: Data‐Independent Acquisition‐Based Quantitative Proteomics Analysis Reveals Dynamic Network Profiles during the Macrophage Inflammatory Response
Author(s) -
Li Lei,
Chen Li,
Lu Xinya,
Huang Chenyang,
Luo Haihua,
Jin Jingmiao,
Mei Zhuzhong,
Liu Jinghua,
Liu Cuiting,
Shi Junmin,
Chen Peng,
Jiang Yong
Publication year - 2020
Publication title -
proteomics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.202070011
Subject(s) - proteomics , quantitative proteomics , front cover , kegg , computational biology , workflow , biology , transcriptome , cover (algebra) , bioinformatics , computer science , gene expression , biochemistry , gene , engineering , database , mechanical engineering
DOI: 10.1002/pmic.201900203 In article number 1900203, Lei Li et al. reveal discrete modules and the signaling network that modulates the development of inflammation. The cover depicts the workflow for DIA‐based quantitative proteomics analysis on the inflammatory response of macrophages challenged with LPS. a) Quality analysis of raw data for quantitative proteomics; b) Analysis on protein expression patterns; c) Sequential analysis of differential expression proteins; d) KEGG pathway analysis with ClueGO of the Cytoscape software; e) Integrated analysis of transcriptomics and proteomics.

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